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With this system, it was shown for two arenaviruses, LCMV and TCRV, that Z was not required for RNA synthesis mediated by the viral polymerase, but rather Z exerted a dose-dependent inhibitory effect on both viral transcription and RNA replication120 122 Through this inhibitory activity, Z might contribute to the known restricted replicative ability and noncytopathic properties of many arenaviruses In natural infection with LCMV, the expression of Z was undetectable during the initial 24 h following infection,121 precisely avoiding a strong negative effect on viral RNA synthesis and allowing virus multiplication to occur Furthermore, Z has also been shown to interact with several cellular proteins The LCMV Z protein was found to bind to the promyelocytic leukemia protein (PML), leading to the relocation of PML nuclear bodies to the cytoplasm.

TABLE 16.1. Security Attacks in Wireless Sensor Networks Spoofed, altered, or replayed routing information Selective forwarding Create routing loop, attract or repel network traf c, extend or shorten source routes, generate false error messages, etc. Either in-path or beneath path by deliberate jamming, allows to control which information is forwarded. A malicious node acts like a black hole and refuses to forward every packet it receives. Attracting traf c to a speci c node for example, to prepare selective forwarding. A single node presents multiple identities, allows us to reduce the effectiveness of fault-tolerant schemes such as distributed storage and multipath. Tunneling of messages over alternative low-latency links to confuse the routing protocol, thereby creating sinkholes, etc. An attacker sends or replays a routing protocols hello packets with more energy.

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On the other hand, you may have reasons that make it preferable to allocate DMA buffers that are cached for instance if you want to perform signi cant data processing on data in the buffer. You can do this using the same example code but with the cache attribute EMapAttrFullyBlocking replaced with EMapAttrCachedMax. However, to maintain cache coherency, you must then ush the cache for each DMA transfer. For a DMA transfer from cacheable memory to peripheral (that is, a DMA write), the memory cache must to be ushed before transfer. The kernel provides the following method for this:

Routing Loops. In sensor networks, routing loops attack the information exchanged between nodes. False error messages are generated when an attacker alters and replays the routing information. Routing loops attract or repel the network traf c and increase node-to-node latency. Selective Forwarding. Selective forwarding is a way to in uence the network traf c by believing that all the participating nodes in network are reliable to forward the message. In selective forwarding attack, malicious nodes simply drop certain messages instead of forwarding every message. Once a malicious node cherry picks on the messages, it reduces the latency and deceives the neighboring nodes that they are on a shorter route. Effectiveness of this attack depends on two factors. First is the location of the malicious node. the closer it is to the base station, the more traf c it will attract. Second is the percentage of messages it drops. When a selective forwarder drops more messages and forwards less, it retains its energy level, thus remaining powerful to trick the neighboring nodes. Sinkhole Attacks. In sinkhole attacks, an adversary attracts the traf c to a compromised node. The simplest way of creating a sinkhole is to place a malicious node where it can attract most of the traf c, possibly closer to the base station or malicious node itself, which deceptively acts as a base station. One reason for sinkhole attacks is to make selective forwarding possible to attract the traf c toward a compromised node. The nature of sensor networks where all the traf c ows toward one base station makes this type of attack more susceptible.

123,124 Z has also been reported to interact with the nuclear fraction of the ribosomal protein P0 and with the eukaryotic translation initiation factor eIF4E125,126 These cellular interactions of Z may provide mechanisms to elucidate a viral strategy for the establishment of chronic infections, a typical property of arenaviruses In addition to its regulatory role during virus replication, the Z protein was also suggested as a virion component with structural functions Based on the segregation of Z as hydrophobic protein associated with viral membranes upon nonionic detergent extraction of LCMV virions,118 Z has been proposed as the arenavirus counterpart of the matrix (M) protein, found in most enveloped negative-strand viruses33,127 The M proteins interact with membranes and are involved in the organization of viral components during assembly and budding, providing a link between the cytoplasmic tail of the glycoproteins and the nucleocapsid that contains the RNA genome.

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